Being social creatures, humans need a safe and secure social environment to exist. For one's physical and emotional well-being, it is imperative to have satisfying social connections. Loneliness may result from a lack of social connections. Intimacy and a sense of belonging are fundamental human desires. Interpersonal connections have several advantages. Loneliness has been perceived as a universal human experience since the dawn. Social connection is essential for everyone's survival. People are innately social beings that rely on one another for assistance. Even though mental health issues and social isolation often coexist in young children, early isolation does not indicate worse mental health issues in the future. However, children with such issues and behaviors could find it difficult to handle the social difficulties they face as they advance through the early years of school. Humans are social animals, and when they don't feel connected, they tend to get sadder, sicker, and more susceptible to developing depression and other mental health problems. Isolation is a frequent occurrence that become more prevalent during the COVID-19 global pandemic, having an adverse effect on people's physical and mental health everywhere. Furthermore, according to the most recent data, there may be an increase in the prevalence of mental health problems among at-risk groups and persons who are vulnerable to them after the pandemic's height. 6 Children and adolescents, the elderly, people who are unemployed or homeless, COVID-19 survivors, people with pre-existing psychiatric conditions, community workers, pregnant women, people who are physically or mentally disabled, migrants, refugees, and members of the LGBT community, as well as people who belong to racial or ethnic minorities, are among the vulnerable populations. Loneliness in the elderly beings and social isolation pose a substantial threat to public health because they increase the risk of dementia and other serious disorders in a huge number of people.